April 4, 2018
The Mass Spectrometry Facility at York University is now fully operational. Please see our updated service offerings in our online Service Requisition Form.
Our LC-MS Proteome profiling development is ongoing and will remain in open public beta until April 31st 2018. This a fantastic opportunity to gain insight into your biological samples at a discounted rate. Please contact the facility if you are interested in participating. A big thanks to the groups who are already participating, your samples are providing invaluable feedback and allowing us to really improve our methodology.
One housekeeping announcement: The Orbitrap Elite will undergo a routine replacement of its Electron Multiplier detectors in April 2018. The instrument will be unavailable for several days. If your samples are scheduled to run on those days, you will be notified ASAP.
We are also excited to announce our next phase of developments will focus on metabolomics. Preliminary method development is scheduled to begin in May 2018, with an open public beta test to immediately follow.
If you have any questions or suggestions regarding the facility and the services we offer, please contact us.
December 7, 2017
Welcome to the Mass Spectrometry Facility at York University. At the moment, the Facility is operating under a “soft start” mode with limited services and capacity for testing.
We are currently developing a number of new methods to enhance our service offering. As new methods and services roll out, we will first announce an open public beta test. This will offer participating groups a chance to evaluate their real samples against our developed methods; providing feedback and allowing us to improve our methodology.
Methods will undergo several rounds of stress testing until they are released as we aim to provide you with the utmost confidence in our methodology and services.
Please see the current Service Requisition Form for a list of our services that are planned, undergoing development, in public beta testing, and in release status.
We look forward to serving both the academic and commercial community. If you have any questions or suggestions regarding the facility and the services we offer, contact us at your leisure.
The Thermo Scientific Orbitrap Elite Mass Spectrometer is a highly sensitive tool that will enable state-of-the-art protein identification and characterization. This research holds promise for breakthroughs in the characterization and early detection of many human diseases, including cancer and cardiovascular disease. This instrument will not only facilitate the identification of complex mixtures of proteins and peptides, but will also enable the identification of posttranslational modifications (PTMs) and the mapping of these sites on targeted proteins. Phosphorylation is one of nature’s most abundant PTMs, which acts as a switch to activate and inactivate protein functions. Thus, this instrument will benefit life and health scientists, and all researchers interested in developing diagnostic and prognostic tools and methods.
A ThermoScientific Easy nLC-1000 nano-flow UPLC.
A Thermo Scientific Orbitrap Elite mass spectrometer equipped with electron-transfer dissociation.
Technical capabilities: MS and MS^n at m/z resolution up to 240,000 fwhm.