The Thermo Scientific Orbitrap Elite Mass Spectrometer is a highly sensitive tool that will enable state-of-the-art protein identification and characterization. This research holds promise for breakthroughs in the characterization and early detection of many human diseases, including cancer and cardiovascular disease. This instrument will not only facilitate the identification of complex mixtures of proteins and peptides, but will also enable the identification of posttranslational modifications (PTMs) and the mapping of these sites on targeted proteins. Phosphorylation is one of nature’s most abundant PTMs, which acts as a switch to activate and inactivate protein functions. Thus, this instrument will benefit life and health scientists, and all researchers interested in developing diagnostic and prognostic tools and methods.
An Eksigent brand “nanoLC ultra 2D” nanoflow high performance liquid chromatography system.
An Eksigent brand “AS-2” autosampler.
A Thermo Scientific Orbitrap Elite mass spectrometer equipped with electron-transfer dissociation.
Technical capabilities: MS and MS^n at m/z resolution up to 240,000 fwhm.