Living organisms can keep gene expression under control
Biology Professor Emanuel Rosonina and co-researchers conducted a study,“Sumoylation controls the timing of Tup1-mediated transcriptional deactivation“, with Columbia University that suggests small ubiquitin (SUMO), a protein that is found in tissue, changes proteins bound to active genes in order to prevent unrestricted gene over-expression that can be dangerous.
As a result of the previous study, SUMO may be important for controlling expression of active genes because it was found on every gene that researchers looked at when turned on.
Seeing that many tumors have unusual levels of SUMO, research states it is important to examine whether unfitting SUMO modification in these tumors are related to uncontrolled gene expression that is found in most cancers.
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