Researchers develop math models to address antibiotic resistance in healthcare facilities
Scientists at York University and a national team of collaborators have developed new mathematical models that will help researchers, doctors and policymakers address the challenging public health issue of antibiotic resistance in bacteria. The research, co-led by postdoctoral fellows Josie Hughes and Xi Huo, was published in the journal PLOS ONE.
“Drug-resistant bacteria, commonly called superbugs, are a really big issue in healthcare facilities because they can spread easily and cause an outbreak,” says a co-author Jianhong Wu, Canada Research Chair and University Distinguished Research Professor at the Faculty of Science at York University. “As you might imagine, it’s hard to contain these infections when treatments are ineffective. And experts worry that it’s only a matter of time before we run out of effective options to treat most infections.”
The team developed math models that focus on a strategy called “antimicrobial de-escalation,” which is widely used in hospitals but poorly understood in terms of its effects.
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